My research interest is to investigate the role of telomeres and telomerase system and epigenetics with adaptation or maladaptation at high altitude hypobaric hypoxia. The relevance of telomere increases because of the prevalence of stress to hypobaric hypoxia at HA. We explored that telomere & telomerase associated genes associated differentially in sojourners/natives and may be potential markers. This study leads for investigation of the association of telomere in extreme environment of hypobaric hypoxia having low pressure, low oxygen and high radiation. Moreover, many diseases are having hypoxia in their pathogenesis including Covid-19 & cancer. So future research objectives are to investigate the association of telomeres and telomerase associated biomarkers in disease pathogenesis of oxidative stress associated diseases including High Altitude disorders, cancer and Covid-19.

My teaching interest is through preparing innovative learning environment through Problem based teaching, Practical based learning, Industrial Exposure, Workshop & Conference based learning. Specific subject teaching done through various case studies. Teaching & research is reflected through peer reviewed publications, disciplined, attentive & Enthusiastic students, Positive feedbacks from the students. Lectures prepared in form of PPT, Study materials, tutorials & Group discussions of the students. Subjects taught in UG, PG & PhD is given hereby.

• M.Sc. Biotechnology & M.Sc. Microbiology: Microbiology, Genomics & Proteomics, Biochemistry, Immunotechnology, Molecular Biology, Cell Technology
• B.Tech. Biomedical Engineering: Microbiology, Genomics & Proteomics, Recombinant DNA Technology, Biochemistry, Molecular Biology, Environmental Studies
• B.Tech. Bioinformatics: Recombinant DNA Technology, Genomics & Transcriptomics, Proteomics, Microbiology
• Ph.D.: Course Work Research Methodology, Research Specialization

Postdoctoral Research (If Any)

• May 2011-Nov 2012-Worked as an ICMR-RA with Dr. Monica Sundd, Scientist at NII, New Delhi.
• June 2009-September 2010-Worked as a NIH-PDF with Dr Hydar Ali, Associate Professor at University of Pennsylvania (Upenn), Philadelphia, PA, USA.
• January 2009-June 2009-Worked as a DBT-PDF with Dr. Dinakar M. Salunke, Senior Scientist at NII, New Delhi.

• Aug 2024-Till Present Professor and Head in Biotechnology & Microbiology & department & Coordinator NPTEL at SRM University, Delhi-NCR, Sonepat.
• June 2018-July 2024-Associate Professor and Head in Biotechnology, Microbiology & Biomedical Engineering  department at SRM University, Delhi-NCR, Sonepat.
• Sept 2014-May 2018-Assistant Professor and Head in Biomedical Engineering & Bioinformatics at SRM University, Delhi-NCR, Sonepat.
• Oct 2013-Sept 2014-Assistant Professor in Biotechnology at Amity University, Haryana.
• May 2011-Nov 2012-ICMR-RA with Dr. Monica Sundd, Scientist at NII, New Delhi.
• June 2009-September 2010-NIH-PDF with Dr Hydar Ali, Associate Professor at University of Pennsylvania (Upenn), Philadelphia, PA, USA.
• January 2009-June 2009-DBT-PDF with Dr. Dinakar M. Salunke, Senior Scientist at NII, New Delhi.
• July 2005-Dec 2008-CSIR-SRF with Dr. MA Qadar Pasha, Senior Scientist at IGIB, CSIR, Delhi
• July 2003-July 2005-CSIR-JRF with Dr. MA Qadar Pasha, Senior Scientist at IGIB, CSIR, Delhi

• Got Approval for DST-SERB-CRG project (CRG/2022/005161) as a Principal Investigator.
• Successfully completed DST-SERB project (SB/YS/LS-155/2014) as a Principal Investigator.
• Three Ph.D. awarded & three Ph.D. ongoing as a Ph.D. Supervisor.
• Corresponding author of high Impact research paper ie. Human Molecular Genetics (IF-6.1) & Drug Discovery Today (IF-7.85)
• Active member as a Treasurer for Hypobaric hypoxia Society since 2021.
• Member of editorial board and Reviewer of many peer- reviewed journals.
• Qualified National Eligibility Test (NET-LS) in Dec-2001 and (NET-JRF) June-2002.
• Invited talk in International Conferences (2010, 2019, 2021 & 2024)
• Qualified Graduate Aptitude Test in Life Sciences (GATE)-2003 with 96 Percentile.
• Topper and Gold Medalist in M.Sc. Biotechnology 2002.
• Qualified DBT-Postdoctoral Fellowship Program 2008-2009, Life Sciences.
• Qualified NIH-Postdoctoral Fellowship Program 2009, for Postdoctoral Research in USA.

Total citation Index: 1902

Total Publication: 48

h-Index- 18

i10- Index- 21

• Rishav Kumar, Ajay Kumar Sharma, Kirti, Aman Kalonia, Priyanka Shaw, M H Yashvarddhan, Arpana Vibhuti, Sandeep Kumar Shukla. Understanding innate and adaptive responses during radiation combined burn injuries. Int Rev Immunol. 2024 Sep 11:1-14. doi: 10.1080/08830185.2024.2402023. Online ahead of print.
• Gajala Deethamvali Ghouse Peer, Anjali Priyadarshini, Archana Gupta, Arpana Vibhuti, Elcio Leal, Antonio Charlys da Costa, Carlos Prudencio, Kirtanjot Kaur, Saheem Ahmad, V. Samuel Raj, and Ramendra Pati Pandey. A Systematic Assessment of Leishmania donovani Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis in India. Microbiology Research. 2024, 15, 1645–1654. https://doi.org/10.3390/microbiolres15030109
• Rahul Kumar, Aastha Mishra, Arpana Vibhuti, Tashi Thinlas, Qadar Pasha. The 7th International Leh Symposium: Lungs at High Altitude: Molecular Mechanisms and Therapeutics of Hypoxic Lung. Pulmonary Circulation, 2024; 14:e70023 doi: 10.1002/pul2.70023
• Gajala Deethamvali Ghouse Peer , Anjali Priyadarshini , Archana Gupta , Arpana Vibhuti , V.Samuel Raj , Chung-Ming Chang, Ramendra Pandey. Exploration of Antileishmanial Compounds Derived from Natural Sources. Antiinflamm Antiallergy Agents Med Chem. 2024 Jan 24. doi: 10.2174/0118715230270724231214112636. Online ahead of print.
• Ajay Kumar Sharma, Aman Kalonia, Rishav Kumar, Kirti, Priyanka Shaw, M H Yashvarddhan, Arpana Vibhuti, Sandeep Kumar Shukla. Alleviation of radiation combined skin injury in rat model by topical application of ascorbate formulation. Int J Radiat Biol. 2024 Feb 2:1-20. doi: 10.1080/09553002.2024.2310016.
• Amit Sharma, Shyam Tripathi, Kusum Rani, Arpana Vibhuti, Ramendra Pati Pandey, V Samuel Raj. The antimicrobial spectrum to manage the co-infections of P. aeruginosa and S. aureus. Research Square 2024 https://doi.org/10.21203/rs.3.rs-5297387/v
• K Sheetal, K Diksha, K Swati, K Tamana, K Baby, Arpana Vibhuti, Archana Gupta, Anjali Priyadarshini, Ramendra Pati Pandey. A New Therapeutic Approach Utilizes Probiotics, Prebiotics, Synbiotics, Postbiotics, and Gut Microbiota. Preprints 2024. doi: 10.20944/preprints202404.1866.v1
• Yogesh Dutt, Ramendra Pati Pandey, Mamta Dutt , Archana Gupta, Arpana Vibhuti, V. Samuel Raj, Chung-Ming Chang, Anjali Priyadarshini. Liposomes and phytosomes: Nanocarrier systems and their applications for the delivery of phytoconstituents. Coordination Chemistry Reviews 2023, 491, 215251.
• Yogesh Dutt, Ramendra Pati Pandey, Mamta Dutt, Archana Gupta, Arpana Vibhuti, Jasmina Vidic, V. Samuel Raj, Chung-Ming Chang & Anjali Priyadarshini. Therapeutic applications of nanobiotechnology. J Nanobiotechnol 2023, 21, 148. https://doi.org/10.1186/s12951-023-01909-z
• Yogesh Dutt, Ramendra Pati Pandey, Mamta Dutt, Archana Gupta, Arpana Vibhuti, V. Samuel Raj, Chung-Ming Chang and Anjali Priyadarshini. Silver Nanoparticles Phytofabricated through Azadirachta indica: Anticancer, Apoptotic, and Wound-Healing Properties. Antibiotics 2023, 12(1), 121; https://doi.org/10.3390/antibiotics12010121
• Gajala Deethamvali Ghouse Peer , Anjali Priyadarshini , Archana Gupta , Arpana Vibhuti , Elcio Leal ORCID logo , Antonio Charlys da Costa ORCID logo , Carlos Prudencio , Chung-Ming Chang ORCID logo , V.Samuel Raj , Ramendra Pandey. A Systematic Assessment of Leishmania donovani Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis OSF Preprint 2023
• Kumar S, Dhiman R, Prudencio CR, da Costa AC, Arpana Vibhuti, Leal E, Chang CM, Raj VS, Pandey RP.Chitosan: Applications in Drug Delivery System. Mini Rev Med Chem 2023, 23 (2), 187-191. doi: 10.2174/1389557522666220609102010.
• Dutt, Y, Dhiman, R, Singh, T, Arpana Vibhuti, Gupta, A, Pandey, R.P, Raj, V.S, Chang, C.-M, Priyadarshini, A. The Association between Biofilm Formation and Antimicrobial Resistance with Possible Ingenious Bio-Remedial Approaches. Antibiotics 2022, 11, 930.
• Siddartha Baliyan, Riya Mukherjee, Anjali Priyadarshini , Arpana Vibhuti , Archana Gupta, Ramendra Pati Pandey, Chung-Ming Chang. Determination of Antioxidants by DPPH Radical Scavenging Activity and Quantitative Phytochemical Analysis of Ficus religiosa. Molecules 2022; 16;27(4):1326.
• Yogesh Dutt, Ramendra Pati Pandey, Mamta Dutt, Archana Gupta, Arpana Vibhuti, V Samuel Raj, Chung-Ming Chang. Synthesis and biological characterization of phyto-fabricated silver nanoparticles from Azadirachta indica. Biomed. Nanotechnol. 2022, Vol. 18(8) 2022-2057. doi:10.1166/jbn.2022.3402
• Anubrata Paul, V Samuel Raj, Arpana Vibhuti. In silico and in vitro Evaluation of Generic Medicines against DENV-2. Journal of Advancement in Pharmacognosy. 2022 2(2);64-72
• Anubrata Paul, Arpana Vibhuti and V Samuel Raj Evaluation of antiviral activity of Andrographis paniculata and Tinospora cordifolia using in silico and in vitro assay against DENV-2. Journal of Pharmacognosy and Phytochemistry. 2021. 10(2), 486-496 DOI: https://doi.org/10.22271/phyto.2021.v10.i2f.13847
• M Miglani, Q Pasha, A Gupta, A Priyadarshni, RP Pandey, Arpana Vibhuti. Seeding Drug Discovery: telomeric tankyrase as a pharmacological target for the pathophysiology of high-altitude hypoxia. Drug Discovery Today 2021;26(11): 2774-2781.
• A Priyadarshini, A Gupta, MK Yadav, Arpana Vibhuti, RP Pandey, VS Raj. Protective Immunity against COVID-19. OSF Preprints, 2021.
• RP Pandey, R Mukherjee, A priyadarshini, A gupta, Arpana Vibhuti, E leal et al. Potential of nanoparticles encapsulated drugs for possible inhibition of the antimicrobial resistance development. Biomedicine &Pharmacothrapy 2021, 141, 111943.
• Anubrata Paul, Arpana Vibhuti, Samuel V Raj. Evaluation of Clinical and Hematological Parameters of Acute Febrile Illness Patients: A Dengue Predictive Model. Model. J Antivir Antiretrovir, 2021, 13 (001)
• A Gupta, A Priyadarshini, MK Yadav, Arpana Vibhuti, VS Raj, RP Pandey. Differential behavior of COVID-19 in Multi-Country Journey: Challenges for Drug Intervention. OSF Preprints , 2021
• A Paul, VS Raj, Arpana Vibhuti, RP Pandey Larvicidal efficacy of Andrographis paniculata and Tinospora cordifolia against aedes aegypti: A dengue vector. Pharmacognosy Research 2020, 12 (4), 352
• RP Pandey, A Gupta, A Priyadarshini,MK Yadav, N Kasturiaa, Arpana Vibhuti, VS Raj.”COVID-19: A Real Killer Disease ”. Indian Journal of Hospital Infection 2020;2(1): 25-28
• Manjula Miglani, Manjari Rain, Qadar Pasha, V Samuel Raj, TashiThinlas, Ghulam Mohammad, Archana Gupta, Ramendra Pati Pandey, Arpana Vibhuti. Shorter telomere length, higher telomerase activity in association with tankyrase gene polymorphism contribute to high-altitude pulmonary edema. Human Molecular Genetics, 2020, 29 (18), 3094-3106
• Pandey RP, Kumar S, Ahmad S, Arpana Vibhuti, Raj VS, Verma AK, Sharma P, Leal E. Use Chou's 5-steps rule to evaluate protective efficacy induced by antigenic proteins of Mycobacterium tuberculosis encapsulated in chitosan nanoparticles. Life Sci. 2020,256, 117961
• Ramendra Pati Pandey, Anjali Priyadarshini, Archana Gupta, Arpana Vibhuti, Elcio Leal, Utpal Sengupta, Vishwa Mohan Katoch, Pawan Sharma, Catrin E Moore, V. Samuel Raj . Exploring the Modulation of Immune Response and Oxidative Stress of Intracellular Pathogens Using Nanoparticles Encapsulating Drugs. 2020, OSF Preprints doi: 10.20944/preprints202010.0580.v1
• Anubrata Paul, Arpana Vibhuti. Dengue Symptoms Significance in Anti-Dengue Drug Development: Road Less Travelled. Bioinformation, 2017, 13(5), 131-135
• Anubrata Paul, Arpana Vibhuti,Samuel V Raj. Molecular docking NS4B of DENV 1-4 with known bioactive phytochemicals. Bioinformation, 2016, 12(3), 140-148
• Anubrata Paul, Arpana Vibhuti, Samuel V Raj. Preliminary Phytochemical Screening of Camellia sinensis &Tinospora cordifolia Used in Traditional Medicine. International Journal of Pharma and Bio Sciences, 2016, 7(2), 187-193
• A Paul, Arpana Vibhuti, S Raj Rise of mosquito bites in India: A comprehensive study on dengue. Asian Pacific Journal of Tropical Disease 2016, 6 (12), 936-939
• Anubrata Paul, Arpana Vibhuti, Samuel V Raj, Jayashree Shaw. Homology Modelling of NS4B Protein of Dengue Using Swiss-PDB Viewer. Indian Journal of Pharmaceutical Science & Research , 2015, 5(4), 205-211
• Arpana Vibhuti, S M paul Khurana. Respiratory Disorders: Is it COPD or Asthma? Science Reporter, NISCARE.June2014
• Aastha Mishra, Zahra Ali, Arpana Vibhuti, Rahul Kumar, PerwezAlam, Rekhbala Ram, Tashi Thinlas, Ghulam Mohammad, MA Qadar Pasha. CYBA and GSTP1 variants associate with oxidative stress under hypobaric hypoxia as observed in high-altitude pulmonary edema. Clinical Science 2012, 122(6), 299-309
• Q Pasha, B Singh, Arpana Vibhuti, E Arif. Genetics of detoxification and oxidative stress pathways in COPD. European Respiratory Journal 2012, 40 (Suppl 56)
• Arpana Vibhuti, Kshitiz Gupta, Hariharan Subramanian, Hydar Ali. Distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of C3a receptor signaling in human mast cells. Plos One, 2011,6(5):e19585.
• Arpana Vibhuti, EhteshamArif, Aastha Mishra, Desh Deepak, Bhawani Singh, Irfan Rahman, Ghulam Mohammad, M A Qadar Pasha. CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. Clinica Chimica Acta, 2010, 411, 474-480
• EhteshamArif, Arpana Vibhuti, Desh Deepak, Bhawani Singh, Mohd Saeed Siddiqui, M A Qadar Pasha. COX2 and p53 risk-alleles coexist in COPD. Clinica Chimica Acta, 2008,397, 48–50
• Arpana Vibhuti, EhteshamArif, Desh Deepak, Bhawani Singh, M A Qadar Pasha. Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD. Biochemical and Biophysical Research Communications, 2007,359, 136-142
• Arpana Vibhuti, EhteshamArif, Desh Deepak, Bhawani Singh, M A Qadar Pasha. Correlation of Oxidative status with BMI and Lung-Function in COPD. Clinical Biochemistry, 2007, 40, 958-963
• EhteshamArif, Arpana Vibhuti, Pervez Alam, Desh Deepak, Bhawani Singh, Mohammad Athar and M.A. Qadar Pasha. Association of CYP2E1 and NAT2 Gene Polymorphisms with Chronic Obstructive Pulmonary Disease. Clinica Chimica Acta, 2007, 382, 37-42
• EhteshamArif, Aarif Ahsan, Arpana Vibhuti, Charu Rajput, Desh Deepak, Mohammad Athar, Bhawani Singh, MA Qadar Pasha. Endothelial Nitric Oxide SynthaseGene Variants Contribute to Oxidative Stress in COPD. Biochemical and Biophysical Research Communications, 2007, 361, 182-188
• M. A. Qadar Pasha, Ehtesham Arif, Arpana Vibhuti. Xenobiotic Metabolizing Gene Variants in a Cigarette-smoke Induced Pulmonary Disease. Perspectives in Cytology and Genetics, 2007, 13, 133-145
• Charu Rajput, EhteshamArif, Arpana Vibhuti, TseringStobdan, Amjad P. Khan, TseringNorboo, Farhat Afrin and M.A. Qadar Pasha. Predominance of interaction among wild-type alleles of CYP11B2 in Himalayan natives associates with high-altitude adaptation. Biochemical and Biophysical Research Communications, 2006, 348, 735-740
• M.A.Q. Pasha, Arpana Vibhuti. Tyr113His, His139Arg of Epoxide Hydrolase and T3801C of Cytochrome P450 1A1 gene polymorphisms associate with Chronic Obstructive Pulmonary Disease. (Abstract Published). Clinica Chimica Acta, 2005,355, S81-201.

BOOK CHAPTERS

• D Ghouse Peer, Anu Saini, Arpana Vibhuti& Amrendra Ajay. Personalized Therapeutics.  Nanotherapeutics for Inflammatory Arthritis, Design, Diagnosis and treatment; 2024; CRC press. ISBN-10 1032391634.
• Shabnam Ahmad, Vandana Dahiya, Arpana Vibhuti, Ramendra Pati Pandey, Manish Kumar Tripathi, Manoj Kumar Yadav. Therapeutic Protein-Based Vaccines.   Protein Based Therapeutics; 2023; Springer.
• Sania Bajaj, Ajay Kumar Sharma, MH Yashavarddhan, Arpana Vibhuti& Sandeep Kumar Shukla. Advancement in Biomarkers Discovery for Elderly Population. Current Challenges and Management of Diseases in the Elderly Populations; 2020; Nova.
• MH Yashavarddhan, Sania Bajaj, SK Shukla, Arpana Vibhuti.Biotransformation: Basics and Applied perspectives. Environmental Microbiology and Biotechnology, 2021, 337-357; Springer.
• V Samuel Raj, A Priyadarshini, MK Yadav, RP Pandey, A Gupta, Arpana Vibhuti. Artificial Intelligence in Bioinformatics. Biomedical Data Mining for Information Retrival: Methodologies, Techniques and Applications 2021; Wiley.
• AK Sharma, P Shaw, A kalonia, MH Yashavarddhan, P Choudhary, SK Shukla,   Recent Perspectives in Radiation-Mediated DNA Damage and Repair: Role of NJEJ and Alternative Pathways. DNA: Damages and Repair Mechanisms, 2021, 99, Intech Open.
• A Nair, Arpana Vibhuti,V Samuel Raj, RP Pandey. RNA-Seq Analysis Strategies to understand viral Pathogenesis. Integrated Omics Approaches to Infectious Diseases, 2021, 185-193; Springer.

EDITED BOOKS

1. Arpana Vibhuti, Chung-Ming Chang, Ramendra Pati Pandey. Antimicrobial Resistance and One Health Approach. 2021 Eliva Press

• University Coordinator NPTEL
• Member Academic Council
• Heading the Biotechnology & Microbiology Department
• Organizing Committee member of International/National Conferences/Seminars organized by SRMUH